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SCIENTIFIC SCORE
Moderately Effective
Based on 1 Researches
8
USERS' SCORE
Good
Based on 7 Reviews
8.5
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B6 (as Pyridoxal-5-Phosphate)
1.5 mg
88%
Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt])
680 mcg DFE‡
170%
Vitamin B12 (as Methylcobalamin)
1,000 mcg
41,667%
Top Medical Research Studies
8
Folate may protect against OSA
The relation of dietary components with severity of obstructive sleep apnea in Cypriot patients: A randomized, stratified epidemiological study.
Folate's impact on sleep apnea
We conducted a thorough investigation into how dietary components, particularly folate, relate to the severity of obstructive sleep apnea (OSA) in a group of adults living in Cyprus. Our study included a diverse sample of 303 participants aged over 18, who completed detailed food frequency and physical activity questionnaires, along with undergoing sleep studies to assess OSA severity.
In our analysis, we found that patients with more severe OSA, identified by a higher apnea-hypopnea index (AHI), had significant characteristics such as increased body mass index (BMI) and higher caloric intake. Interestingly, those with moderate to severe OSA reported higher folic acid consumption compared to those with milder forms of the condition.
This suggests that while greater energy intake appears to correlate with more severe OSA, a higher intake of folate may offer some protective benefits. However, it’s essential to note that we did not isolate the effects of folate alone, as other dietary factors were also at play in our findings, making further research necessary to draw stronger conclusions.
Overall, our results point towards the complexity of dietary influences on sleep apnea severity, highlighting folate as a potentially beneficial nutrient alongside other lifestyle factors.
In our analysis, we found that patients with more severe OSA, identified by a higher apnea-hypopnea index (AHI), had significant characteristics such as increased body mass index (BMI) and higher caloric intake. Interestingly, those with moderate to severe OSA reported higher folic acid consumption compared to those with milder forms of the condition.
This suggests that while greater energy intake appears to correlate with more severe OSA, a higher intake of folate may offer some protective benefits. However, it’s essential to note that we did not isolate the effects of folate alone, as other dietary factors were also at play in our findings, making further research necessary to draw stronger conclusions.
Overall, our results point towards the complexity of dietary influences on sleep apnea severity, highlighting folate as a potentially beneficial nutrient alongside other lifestyle factors.
Read More
Most Useful Reviews
9.5
Better sleep achieved
I initially took B12 to address my deficiency, but to my delight, it also improved my sleep. I now fall asleep quickly, which was a problem before, even with other medications.
Read More
9
Improved sleep quality
My MCV value returned to normal, and my sleep quality has significantly improved. After taking half a sublingual tablet of B12 after each meal for a month and a half, I noticed remarkable progress. I now sleep through the night without waking, and I feel less irritable. It’s been a relief to experience no colds for the first time. Although it’s not cheap, I'm delighted with the results. I plan to continue as I hold hope for improving my memory further.
Read More
7.5
Less anxiety experienced
After three years of a strict vegan diet, my B12 levels were low, but following a month's use of this complex, my levels rose to near normal. I've also noticed better sleep and a reduction in anxiety, especially when engaging in sports.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Researches
8
8
Folate may protect against OSA
The relation of dietary components with severity of obstructive sleep apnea in Cypriot patients: A randomized, stratified epidemiological study.
Folate's impact on sleep apnea
We conducted a thorough investigation into how dietary components, particularly folate, relate to the severity of obstructive sleep apnea (OSA) in a group of adults living in Cyprus. Our study included a diverse sample of 303 participants aged over 18, who completed detailed food frequency and physical activity questionnaires, along with undergoing sleep studies to assess OSA severity.
In our analysis, we found that patients with more severe OSA, identified by a higher apnea-hypopnea index (AHI), had significant characteristics such as increased body mass index (BMI) and higher caloric intake. Interestingly, those with moderate to severe OSA reported higher folic acid consumption compared to those with milder forms of the condition.
This suggests that while greater energy intake appears to correlate with more severe OSA, a higher intake of folate may offer some protective benefits. However, it’s essential to note that we did not isolate the effects of folate alone, as other dietary factors were also at play in our findings, making further research necessary to draw stronger conclusions.
Overall, our results point towards the complexity of dietary influences on sleep apnea severity, highlighting folate as a potentially beneficial nutrient alongside other lifestyle factors.
In our analysis, we found that patients with more severe OSA, identified by a higher apnea-hypopnea index (AHI), had significant characteristics such as increased body mass index (BMI) and higher caloric intake. Interestingly, those with moderate to severe OSA reported higher folic acid consumption compared to those with milder forms of the condition.
This suggests that while greater energy intake appears to correlate with more severe OSA, a higher intake of folate may offer some protective benefits. However, it’s essential to note that we did not isolate the effects of folate alone, as other dietary factors were also at play in our findings, making further research necessary to draw stronger conclusions.
Overall, our results point towards the complexity of dietary influences on sleep apnea severity, highlighting folate as a potentially beneficial nutrient alongside other lifestyle factors.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.5
9.5
Better sleep achieved
I initially took B12 to address my deficiency, but to my delight, it also improved my sleep. I now fall asleep quickly, which was a problem before, even with other medications.
9
Improved sleep quality
My MCV value returned to normal, and my sleep quality has significantly improved. After taking half a sublingual tablet of B12 after each meal for a month and a half, I noticed remarkable progress. I now sleep through the night without waking, and I feel less irritable. It’s been a relief to experience no colds for the first time. Although it’s not cheap, I'm delighted with the results. I plan to continue as I hold hope for improving my memory further.
Read More
8.3
Improved sleep quality
I purchased this for my son to address his sleep quality issues due to work stress, and it has effectively helped him.
8
Enhanced energy levels
I found this product to provide energy and help combat lethargy, leading to improved sleep quality.
7.5
Less anxiety experienced
After three years of a strict vegan diet, my B12 levels were low, but following a month's use of this complex, my levels rose to near normal. I've also noticed better sleep and a reduction in anxiety, especially when engaging in sports.
